AIM-HIV PROJECT------------------------Instituto Salud Carlos III


The specific objectives of the project are:

  • To investigate the antiviral activity of 5HT by using innovative cellular and mucosal models and techniques,

  • To depict the mechanism of action of 5HT,

  • To identify the anti-inflammatory capacity of the  compound,

  • To assess the efficacy and pharmacokinetics of 5HT in animal models,

  • To investigate the synergism of 5HT with other microbicides and antiretroviral drugs,

  • To obtain the most appropriate formulation of 5HT,

  • To design exploitation strategies that take into account the specific regulatory and social characteristics,

  • To develop an optimized, low-cost and highly stable microbicide for its subsequent distribution in African countries.

NEWS 01  


Productive HIV-1 infection of human cervical tissue ex vivo is associated with the secretory phase of menstrual cycle. Read more.    




10/01/2014. The partners of the project and the Scientific Advisory Board attended the Progress Meeting of the project in Madrid.  



October 7-10, 2013. ISCIII and SEPROX presented an oral communication and a poster in the AIDS Vaccine Conference. Read more.


Instituto de Salud Carlos III. 2013. All rights reserved

This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 305938.

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